Archive for January, 2021

Vitamin E (Tocopherol) Biochemistry: Sources, Daily requirements, Functions, Deficiency and Toxicity

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Vitamin E (Tocopherol) Biochemistry: Sources, Daily requirements, Functions, Deficiency and Toxicity

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Vitamin E (Tocopherol): Sources, Daily requirements, Functions, Deficiency Symptoms, and Toxicity

Characteristics
————————
Synonyms: tocopherol, tocotrienols
Active form: tocopherol
Sources: meat, eggs, vegetable oils, leafy vegetables[7]
Transport: alpha-tocopherol transfer protein (α-TTP)
Storage: adipose tissue, parenchymal cells of the liver

Functions
—————-
Antioxidant
Protection from free radicals, especially erythrocytes and cell membranes
Interrupts free radical chains and oxidizes itself as a result

Other functions
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Inhibition of platelet aggregation, cell proliferation, and monocyte adhesion
Enzyme inhibition (e.g., protein kinase C, phospholipase A2)
Inhibition of gene transcription (e.g., for α-TTP, tropomyosin alpha-1 chain)

Vitamin E deficiency
———————————
Deficiency is very rare
Causes
Fat malabsorption disorders (e.g., cystic fibrosis)
Defects in genes that code for α-TTP

Clinical features
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Neurologic dysfunction
Demyelination of the posterior column and spinocerebellar tract → ↓ proprioception and vibration sensation; ataxia → symptoms similar to vitamin B12 deficiency
Differentiation from vitamin B12 deficiency: lack of hypersegmented neutrophils, megaloblastic anemia, and increased methylmalonic acid levels
Hemolytic anemia: deficiency results in increased fragility of erythrocytes and membrane breakdown
Acanthocytosis
Muscle weakness

Vitamin E toxicity
—————————–
Toxicity is very rare
Causes: over-supplementation
Clinical features
In infants: increased risk of necrotizing enterocolitis (NEC)
Alteration of warfarin metabolism → increased anticoagulation → increased risk of bleeding
Increased incidence of heart failure, subarachnoid hemorrhage, and increased mortality
Therapeutic uses
Non-alcoholic steatohepatitis: consider vitamin E for antioxidant effect

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Some benefits tips for bitter foods that are good for your health

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Vitamin B12, B1 & B2 Benefits In Urdu/Hindi | COVID-19 Immunity Boosting Foods | Vitamin B Ke Fayde

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Coronavirus (COVID-19) pandemic is affecting every aspect of our lives, from telecommuting to work from home to country’s lock down. Observing public health measures and reducing exposure to the virus are required to slow the spread of this disease.

No one knows how long this coronavirus (COVID-19) safety measures will need to stay in place, but it presents a perfect time to protect and improve your health while practicing social distancing. Healthy eating is especially important for keeping your immune system in top condition. One such important nutrient to boost the immune system is Vitamin B. To book a personal appointment with a dietitian visit the following links:

https://oladoc.com/pakistan/lahore/nutritionist?utm_source=youtube&utm_medium=referral&utm_campaign=Ayesha_Nasir&utm_content=Immunity_Boosting
https://oladoc.com/pakistan/karachi/nutritionist?utm_source=youtube&utm_medium=referral&utm_campaign=Ayesha_Nasir&utm_content=Immunity_Boosting
https://oladoc.com/pakistan/islamabad/nutritionist?utm_source=youtube&utm_medium=referral&utm_campaign=Ayesha_Nasir&utm_content=Immunity_Boosting

Vitamin B play a vital role in maintaining good health and well-being. As the building blocks of a healthy body, Vitamin B have a direct impact on your energy levels, brain function, and cell metabolism.

In this video, Ms. Ayesha Nasir, an expert Nutritionist from Lahore is giving advice in Urdu/Hindi, on foods that are rich in Vitamin B and how you can include them in your healthy diet. The Vitamin B rich foods can help to boost your immunity to fight against coronavirus (COVID-19). If you or anyone in your family are worried about the coronavirus please visit a doctor and get yourself tested.

Ms. Ayesha Nasir is a Dietitian practicing at Cosme Studio (DD Block, DHA) Lahore. Ms. Ayesha is also available for Online Video Consultation at oladoc.com. To book an appointment with Ms. Ayesha, please visit the following link or call 042-3890-0939.

https://oladoc.com/ayesha-nasir-dietitian/?utm_source=youtube&utm_medium=referral&utm_campaign=Ayesha_Nasir&utm_content=Immunity_Boosting
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Do you get enough B vitamins in your diet? Be active in knowing whether you should treat or supplement with Vitamin B. Well, you might be asking right now; what exactly is the difference? To answer this question and so much more, we are joined in studio by Pharmacist Tshepo Seforo.

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